As we know – PCOS is POLYCYSTIC OVARIAN SYNDROME which represents with irregular menses, skin manifestation and infertility. India is considered as a hub for PCOS with every zone of India having 12-16% of incidence. Every 6th Infertile couple has PCOS. Therefore it is a question of worry and thus we need to discuss – weather is it really tough or a blessing in fertility treatment to have PCOS in current scenario. As we know that in PCOS, IUI gives 13 -20 % of cumulative pregnancy rate after 6 cycles. But in PCOS ovary is very sensitive to stimulation and IUI stimulation is never controlled properly by any hormone. Apart from results, multiple pregnancy cannot be controlled by IUI Treatment , where ovarian hyper-stimulation is one of the threat behind the treatment. After the invention of the antagonist injection in IVF Treatment , which overall controls the hyper-stimulation by 75 -85% followed by the strategy of giving lupride injection of ovulation trigger ...