What is personalized approach in IVF?

Let me try and put this entire concept in a layman terminology. The ability to grow a healthy plant requires a good seed be planted in a fertile soil. Then it requires proper nurturing till it thrives. Similarly, successful IVF requires the same relationship. A good seed is a competent, chromosomally normal embryo and fertile soil is a receptive uterine lining.

Step by step approach in this concept can be as under:

• It is important to define the variables that affect embryo quality and uterine receptivity for each patient

• To avoid "one size fits all" protocols for controlled ovarian stimulation. Instead it is necessary to individualize the protocol to fit the profile of each individual so as to establish an optimally nurturing environment for developing follicles, eggs and uterine lining.

• To precisely time the egg retrieval (ER) and then safely extract, eggs from the woman's ovary.

• Provide the environment for the embryo to grow till the 5th day. Along with this PGT is must in cases of advanced maternal age and repeated failure cases. Another genetic testing called ERA is used to know the exact transfer window period of each patient. This test has shown great promise even in case of a single failure cases.

Finally, to increase the chances of implantation, it is in the interest of the patient to go for scratching of the endometrium. It has shown good results with increase in the endometrial thickness. So by the use of advanced genetic biomarkers for individualised stimulation, hormone(FSH & LH) receptor, Euploid chromosomally normal embryo (PGT) and in even single implantation failure with the help of ERA, we can move towards single embryo transfer.

Best IVF Center in Ahmedabad - Wings Hospitals

Comments

How can we treat zero sperm count...???

Male Infertility increased day by day in which out of 50-100 percent of patients can get pregnancy by their own sperm. 2 variety can be seen in the population : 1) problem in production 2) travelling obstruction Maximum result and confidence can be explained to those who are having obstruction.which means there will be a obstruction from testis to ejaculation in the travelling component. So Doctor can obtain sperm by small needle aspiration. In difficult condition we can do Micro Tessa to retrieve best sperm.The most difficult scenario is problem in production. Our strong belief is to give minimum two month medical management on the basis of testosterone and estrogen. 25-30 percent can retrieve healthy sperm by a technique MicroTessa if required.we offer only Day 5 transfer and PGS & ERA in a recurrent failure and previous two abortion cases. Best Infertility Treatment in Ahmedabad - Wings Hospitals

The prevalence and management of Endometriosis.

Endometriosis is the disease in which endometrium, i. e. the tissue that normally lines the uterus or womb, happens to grow outside of the uterus and on other areas in the body where it doesn’t belong. Total incidence is 1-2%. Usually the patients with endometriosis tend to have a very strong mental constitution, high achiever and usually very competitive with themselves. Common signs and symptoms are painful periods, pain with intercourse, pain during urination and defecation, infertility and excessive bleeding. In short, endometriosis is a chronic disease that causes severe pain and fertility problems. Endometriosis is of minimal, mild, moderate and severe stages. The most common sites affected are the pelvic peritoneum and ovaries. Diagnosis is through transvaginal ultrasound, rectal endoscopical ultrasound, 3 D ultrasound or by MRI. Surgery is required only in patients with more than 4 to 6 cm lesions accompanied by severe pain....

True Facts of IVF treatment in today’s era.

I m sharing my personal experience today that to make sure that certain wrong things are not implemented in IVF treatments . Polycystic ovary patient with one time ovarian hyper stimulation should not happen in today’s era. Because of the previous hyper stimulation patient should not accept egg donation.Early move towards IVF treatment is a future in PCOS patients. Limit number of IUI to not more than 3 attempts.When patient is having 0 count in semen analysis, they should not accept sperm donation straight forward without biopsy. 50 percent men can retrieve sperm. Micro Tesa and Micro Pesa is the latest advancement in technology. Transferring embryos repeatedly will not improve pregnancy rate. Repeated trials is not the way forward. Money binding scheme are non scientific and will promote more of unnecessary egg donation. Don’t accept egg donation quickly at any low AMH levels. It is challenging to give pregnancy at any low AMH but it requires experience and tech...

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